UJean-François Toussaint, intloko kaSanofi Pasteur kuphando kunye nophuhliso lwehlabathi, ulumkise ukuba impumelelo yogonyo lwe-mRNA ngokuchasene ne-Covid ayiqinisekisi iziphumo ezifanayo zomkhuhlane.
“Kufuneka sithobeke,” watsho."Idatha iya kusixelela ukuba iyasebenza."
Kodwa ezinye iiphononongo zibonisa ukuba izitofu zokugonya ze-mRNA zinokungqina ukuba zinamandla kunezemveli.Kuphononongo lwezilwanyana, izitofu zokugonya ze-mRNA zibonakala zibonelela ngokhuselo olubanzi ngokuchasene neentsholongwane zomkhuhlane.Bakhuthaza amajoni omzimba ezilwanyana ukuba enze amajoni omzimba ngokuchasene nentsholongwane, kwaye aqeqeshe iiseli zokhuselo lomzimba ukuba zihlasele iiseli ezosulelekileyo.
Kodwa mhlawumbi eyona nto ibalulekileyo kumkhuhlane, izitofu zokugonya ze-mRNA zinokwenziwa ngokukhawuleza.Isantya sokwenziwa kwe-mRNA sinokuvumela abenzi besitofu sokugonya ukuba balinde iinyanga ezimbalwa ezongezelelweyo ngaphambi kokuba bakhethe ukuba zeziphi iintlobo zomkhuhlane abanokuzisebenzisa, ezinokukhokelela kumdlalo ongcono.
UGqr. Philip Dormitzer, igosa eliyintloko lezenzululwazi kwi-Pfizer uthi: “Ukuba ubunokuqinisekisa ngama-80 ekhulwini minyaka le, ndicinga ukuba oko kuya kuba luncedo olukhulu kwimpilo yoluntu.
Itekhnoloji ikwenza kube lula kubenzi bogonyo lwe-mRNA ukuba benze iishothi ezidityanisiweyo.Kunye neemolekyuli ze-mRNA kwiintlobo ezahlukeneyo zomkhuhlane, zinokongeza iimolekyuli ze-mRNA kwizifo zokuphefumla ezahlukeneyo.
Kumboniso we-9 kaSeptemba wabatyali-mali, uModerna wabelana ngeziphumo zovavanyo olutsha apho abaphandi banike amayeza okugonya iimpuku adibanisa ii-mRNAs zeentsholongwane ezintathu zokuphefumla: umkhuhlane wonyaka, i-Covid-19 kunye ne-pathogen eqhelekileyo ebizwa ngokuba yintsholongwane yokuphefumla ye-syncytial, okanye i-RSV.Iimpuku zavelisa amanqanaba aphezulu ezilwa-buhlungu ezichasene nazo zontathu iintsholongwane.
Abanye abaphandi bebekhangela isitofu sokugonya somkhuhlane jikelele esinokukhusela abantu iminyaka emininzi ngokukhusela uluhlu olubanzi lweentlobo zomkhuhlane.Esikhundleni sokudubula ngonyaka, abantu banokufuna i-booster kuphela emva kweminyaka embalwa.Kweyona meko ilungileyo, ugonyo olunye lusenokusebenza ubomi bonke.
KwiDyunivesithi yasePennsylvania, iqela labaphandi elikhokelwa nguNorbert Pardi liphuhlisa izitofu zokugonya ze-mRNA ezifaka iiproteni ezisuka kwiintsholongwane zomkhuhlane eziguquka nje kunqabile.Uvavanyo lwezilwanyana lubonisa ukuba ezi zitofu zinokuhlala zisebenza unyaka nonyaka.
Nangona iModerna ingasebenzi kwisitofu sokugonya umkhuhlane okwangoku, "yeyona nto sinomdla kuyo kwikamva," utshilo uGqr. Jacqueline Miller, intloko yenkampani yophando lwezifo ezosulelayo.
Nokuba izitofu zokugonya zomkhuhlane we-mRNA ziphila ngokulindelekileyo, ziya kudinga iminyaka embalwa ukufumana imvume.Uvavanyo lokugonya umkhuhlane we-mRNA aluyi kufumana inkxaso enkulu karhulumente eyenziwe ngamayeza okugonya e-Covid-19.Kananjalo nabalawuli abayi kubavumela ukuba bafumane ugunyaziso olungxamisekileyo.Umkhuhlane wexesha elithile awusosisongelo sitsha, kwaye sele unokubalwa namayeza okugonya anelayisensi.
Ke abavelisi kuya kufuneka bathathe indlela ende ukuya kulwamkelo olupheleleyo.Ukuba amalingo onyango okuqala ahamba kakuhle, abenzi bamayeza emva koko kuya kufuneka baqhubele phambili kulingo olukhulu olunokufuna ukunwenwa ngamaxesha amaninzi omkhuhlane.
“Ifanele isebenze,” watsho uGqr. Bartley weYunivesithi yaseConnecticut."Kodwa ngokucacileyo yiyo loo nto senza uphando-ukuqinisekisa ukuba 'kufanele' kwaye 'senza' yinto enye."
Ixesha lokuposa: Apr-21-2022